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Paper Details

A facile Microwave Induced synthesis of some novel 3- [4-(4-nitrophenoxy)-phenyl]-5-(substituted aryl)-2- pyrazoline-1-carboxaldehydes as potential antimicrobial agents

Priya Gothwal and Y. K. Srivastava*

Journal Title:Journal of Chemical, Biological and physical sciences

In the present communication, a series of some novel 3-[4-(4-nitrophenoxy)-phenyl]-5-(substituted aryl)-2-pyrazoline-1-carboxaldehydes have been synthesized by the treatment of substituted 4-(4- nitrophenoxy) chalcones (1a-f) with hydrazine hydrate in hot formic acid under microwave irradiation in 80-85% yield with high purity. The newly synthesized compounds were confirmed by the spectral analysis and elemental data. These compounds were evaluated for their antimicrobial activities.