Pyrazoline-Piperazine merged Compounds: Synthesis, spectral analysis and antibacterial evaluation
Kokila Parmar*1, Jayendra Singh Vihol1, Yogesh Dabhi, 2and Viral Modi3
Journal Title:Journal of Chemical, Biological and physical sciences
Ten new flurine-containing 2-[4-(4-flourophenyl) piparazine-1-yl-methyl]-3,5-substituted phenylpyrazoline
(3a-j) have been synthesized in 80-85% yield by a condensation of various chalcones with
hydrazine hydrate. The structures of the synthesized compounds were confirmed by UV, IR, 1H NMR
and Mass spectral data. The Compounds were evaluated for in vitro antibacterial activity.