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Paper Details

Pyrazoline-Piperazine merged Compounds: Synthesis, spectral analysis and antibacterial evaluation

Kokila Parmar*1, Jayendra Singh Vihol1, Yogesh Dabhi, 2and Viral Modi3

Journal Title:Journal of Chemical, Biological and physical sciences

Ten new flurine-containing 2-[4-(4-flourophenyl) piparazine-1-yl-methyl]-3,5-substituted phenylpyrazoline (3a-j) have been synthesized in 80-85% yield by a condensation of various chalcones with hydrazine hydrate. The structures of the synthesized compounds were confirmed by UV, IR, 1H NMR and Mass spectral data. The Compounds were evaluated for in vitro antibacterial activity.