In-vitro Antimalarial Evaluation of Novel Functionalized Chalcones
Kunwarvir Singh1, Amit Sahu2, Manisha3* and Lal Singh1
Journal Title:Journal of Chemical, Biological and physical sciences
Novel chalcones have been synthesized by conventional method. They were evaluated for their invitro
antimalarial activity against chloroquine sensitive strain of Plasmodium falciparum (NF-54).
Of the 14 compounds synthesized, 3 compounds viz, 6f, 6g and 7g were found to be most potent
and shown IC50 values in the range 2-9 ?g/mL.