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Paper Details

Negative ion mode mass spectrometry- an overview

Pavani Challamalla, Somsubhra Ghosh*, N. Parthiban, K. N. V Rao and David Banji.

Journal Title:Journal of Chemical, Biological and physical sciences

Negative ion mode Mass spectrometry is the most comprehensive and versatile tool. Recent advances in negative ion mode mass spectrometry have improved sensitivity, identification and elucidation of organic and inorganic compounds. All compounds will not produce negative ions but many important compounds of environmental or biological interest can produce negative ions under the right conditions. For such compounds, negative ion mode mass spectrometry is more efficient, sensitive and selective than positive ion mass spectra. In this review, discuss the overall framework of the negative ion mode mass experiments into its key components, such as principle, ionization techniques, instrumentation, fragmentation and applications.