Evaluation of In-Vitro Antihelminthic Activity of Aconitum Heterophyllum
Aditya M. Pattewar*, Pandharkar T.M, Yerawar P.P. and Patawar V.A.
Journal Title:Journal of Chemical, Biological and physical sciences
This study involves the evaluation and comparison of invitro anthelmintic activity of alcoholic and
aqueous extracts of root of traditional medicinal plant Aconitum heterophyllum belongs to family
Ranunculaceae against Pheritema postuma most commonly known as an Indian earthworm.
Extraction was done by Soxhelation and Maceration for extraction of alcoholic and aqueous extract
respectively. Various dilutions of extracts were prepared as in concentration range of 10%, 20%, 40%,
60%, 80%, and 100%, all dilutions were screened for in-vitro antihelmintic activity against Pheritema
postuma; piperazine citrate was used as standard. The observations were recorded as time required
for first three attacks of paralysis and time required for complete death of parasites. The results of
study conclude that plant Aconitum heterophyllum possess good anthelmintic potential particularly at
dose of 100%. Study can be further extended as to find out exact chemical constituent responsible for
anthelmintic activity so as to improve potency of extract.