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Paper Details

Synthesis and in Vitro Antibactarial and Anti Fungal Activity of Trisubstituted S-Triazines

Anil Rathavi*, Maharshi Shukla, 1M. K. Thakor

Journal Title:Journal of Chemical, Biological and physical sciences

Ten compounds have been synthesized in a series of [1, 3, 5] triazine analogues which, in addition to 9-ethyl-9H carbazol-3-amine, contain morpholine and different Amines as well as piperidine substituents on the C-6 position of s-triazine ring. The title compounds were then evaluated for their in vitro microbial activity against 2 gram Ve bacteria (E.coli, P. aeruginosa), 2 gram +Ve bacteria (S. aerues, B. subtilis) and 2 fungal species (C. albicans and A. niger). The most of the synthesized compounds have shown promising antimicrobial activity. All the final compounds were structurally elucidated on the basis of IR, 1H NMR, and other elemental analysis.