Preparation, Modification and Characterization of a Hydrogel Based on Polyacrylic and Polymetacrylic Acid as a Potential Carrier for Drug Delivery Systems
Voycheva C*, Georgiev V, Natova M and Baranovsky VY
Journal Title:Open Access Journal of Pharmaceutical Research
Complexes of polyacrylic acid (PAA) and polymethacrylic acid (PMA) in presence of sodium alginate (SAL) during redox polymerization of polyacids were formed. They were characterized by IR spectroscopy and viscometry. The swelling index of hydrogels based on the polymethacrylic acid-sodium alginate complex (PMA-SAL) has been found to be lower than that of polyacrylic acid-sodium alginate (PAA-SAL) complex. The hydrogels based on the complex of crosslinked polyacids with sodium alginate can be of practical interest as polymeric carriers for drugs.