Invitro Anthelmintic Efficacy of Aqueous Extract of Parkiabiglobosa Fruit Husk on Albino Rats
Telta, D.; Dibila, H. M.; Ojo, N. A.; Sanni, S.; Sandabe, U. K. and Shamaki, B. U.
Journal Title:Journal of Environmental Issues and Agriculture in Developing Countries
The toxicity and anthelmintic efficacy of the aqueous extract of Parkiabiglobosa fruit husk were studied in albino rats. The oral acute toxicity study was conducted using the standard method. The anthelmintic efficacy of the extract was conducted using the fecal and larval recovery test tube paper technique and the egg hatch assay. The result of the studies showed that the LD50 of the oral administration of the extract was 1120mg/kg b.w indicating that the extract was moderately toxic. The extract did not significantly reduce egg hatch as compared to levamisol and albendazole used in this study, hence does not have anthelmintic effect. In conclusion the aqueous extract of Parkiabiglobosa fruit husk can be said to be safe but does not possess anthelmintic activity.