In-Vitro Comparative Quality Evaluation of Marketed Cefuroxime 250 mg Tablets in Bangladesh
Md. Shahin Sarker1*, Md. Rafiqul Islam1, Md. Selim Reza1, and Mir Imam Ibne Wahed2
1Department of Pharmacy, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore-7408, Bangladesh; 2Department of Pharmacy, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh
Journal Title:European Journal of Medical and Health Sciences
The study evaluated different quality control parameters of five brands of Cefuroxime 250mg tablets which are already marketed in Bangladesh. Five brands of the drug sourced from different retail outlets to assess the quality assessment and comparison of the tablets using the in-vitro release study. The brands were subjected to various official tests including uniformity of weight, thickness test, dissolution tests, and cumulative % of drug release and friability test. This research further focuses on the requirement of manufacturers to construct quality into their products during manufacture and also sustain the built-in quality from batch to batch in line with the principles of cGMP.