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Paper Details

Antibacterial Activity of Cissus quadrangularis Stem Extract on the Pathogenic and Industrial Waste Watered Bacteria  

Md. Golam Mosaib1*, Md. Abdullah Al Maruf2, Rabiul Islam3, Shahriar Mahmud4, Shaharuq Nahid Sohana4, Md. Abu Sayeed Imran4, Mehadi Hasan Rony4, Maidul Islam5, Fatema Tuz Zuhora6, and Shafiqul Islam6   1Dept. of Biochemistry and Molecular Biology, Gono Bishwabidyalay, Savar, Dhaka, Bangladesh; 2Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka, Bangladesh; 3Divisional DNA Screening Laboratory, Faridpur Medical College Hospital, Ministry of Women & Children Affairs, Faridpur, Bangladesh; 4Dept. of Biotechnology and Genetic Engineering, Islamic University, Bangladesh; 5Apex Biotechnology Laboratory, Dhaka, Bangladesh; and 6Dept. of Microbiology, Gono Bishwabidyalay, Savar, Dhaka, Bangladesh *Correspondence: gmosaib@gmail.com  

Journal Title:European Journal of Medical and Health Sciences

Cissus quadrangularis (Vitaceae) is a popular climber conspicuous by its flesh quadrangular stem widespread throughout Bangladesh. The in vitro antimicrobial activity of C. quadrangularis extracts was studied against selected pathogenic bacteria, industrial wasted bacteria, and broth dilution assay. The most commonly used method of microbiological assay is the disc diffusion method. C. quadrangularis stem extracted with four solvents (Petroleum spirit, methanol, ethyl acetate, and dichloromethane) were tested for antimicrobial activities against some pathogenic microorganisms  Sarcina lutea (002-1), Xanthomonas campestris (004-1), Escherichia coli (005-1), Klebsiella pneumonia (006-1) and some industrial (Tannery, Tobacco, and Sugar mill) waste watered bacteria by disc diffusion method. Among the four extracts, ethyl acetate showed moderate antibacterial activity against X. campestris (004-1) and industrial watered bacteria. But, the commercial disc Oxicycline doesn’t show any antibacterial activity against the industrial waste watered bacteria. Petroleum spirit, methanol, and dichloromethane extract were ineffective against all of the tested bacteria.