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Paper Details

A Triple Negative Breast Cancer That Does Not Require Chemotherapy: A Case Report of Adenoid Cystic Carcinoma of the Breast

Mohammed Al Duhileb1* , MD; Jamila Alazhri1, MD; Miral Mashhour2, MD; Ahmed Alwbari3, MD *Corresponding author: Dr Mohammed Al Duhileb, Breast and endocrine surgery, King Fahad Specialist-Dammam. Saudi Arabia.

Journal Title:Annals of Case Reports & Reviews

Background: Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm accounting for 0.1%. It is of special interest because of its favorable prognosis and unique management approach.                        Case Presentation: A 42-year-old female presented with a palpable lump in the left breast. Tru-cut biopsy revealed invasive ductal carcinoma ACC form. A breast conserving surgery with sentinel lymph node biopsy were performed. Histopathology revealed ACC with estrogen receptor negative, progesterone receptor negative and HER2-Neu negative type. The multidisciplinary tumor board recommended that neither neoadjuvant nor adjuvant systemic treatment to be offered to this patient. She received adjuvant radiation therapy. In this report, we present a comprehensive review of the literature and discuss the unique characteristics of ACC, its prognosis compared to other triple negative breast cancer subtypes, and the evidence as well as the controversy in different treatment approaches.  Keywords: Adenoid Cystic Carcinoma, Breast Cancer.