An Overview of the Drug Susceptibility Testing for Tuberculosis
Vikas Jha, BS Ajit Kumar, Sampurna Panigrahi, Gayatri Nair and Nikitha Bangera.
Journal Title:Acta Scientific Microbiology
There in an increase in demand for reliable, inexpensive and rapid drug susceptibility assay because of expanding anti-tuberculosis drug-resistant Mycobacterium tuberculosis necessitating the need for appropriate treatment. One of the major challenges being faced is the lack of resources and the limiting of reliable drug susceptibility test meeting acceptable levels only for isoniazid and rifampicin. In this article, an overview of different drug susceptibility testing and assays is detailed and the advantages and disadvantages highlighted. It discusses the perspective on conventional methods which have paved the way for modern DSTs along with the advancements made in the conventional methods.