Changing Patterns of Methicillin-Resistant Staphylococcus aureus in a Tertiary Care Hospital
Ambreen Shafaat Khan, Tarana Sarwat, Sneha Mohan, Mariyah Yousuf and Dalip Kakru
Journal Title:Acta Scientific Microbiology
Background:Methicillin resistance in Staphylococcus aureus is associated with multi drug resistance. In hospitals and community mortality and morbidity rate increases due to MRSA. Methicillin resistant Staphylococcus aureus (MRSA) results in serious complica-tions. Methicillin sensitive strains are less problematic than MRSA.
Aim:To study the changing trends in resistance patterns of MRSA.
Materials and Methods:Fifty eight clinical isolates of MRSA which were obtained in 2017 - 2020 were identified by using Cefoxitin disc according to CLSI guidelines.
Results: MRSA isolates showed high resistance to ciprofloxacin, gentamicin in comparison with other drugs. Sensitivity to Vancomy-cin and Linezolid was 100%. Recently resistance among MRSA has increased for most antibiotics.
Conclusion:As the rate of drug resistance in MRSA is increasing, resistance should be evaluated after a period of time and antibiotic therapy should be guided accordingly.
Keywords:Methicillin Resistant Staphylococcus aureus; Multi Drug Resistance; Cefoxitin