Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)
Iman Ibrahim Mohamed Eladawy 1; Amal Beshr2; Reda Behairy3; Alaa Ameen4
1ENT Department, faculty of medicine for girls (Cairo) , Al-azhar University
2ENT Department, Faculty of medicine for girls (cairo) , Al-azhar University
3ENT Department, faculty of medicine, for girls (cairo), Al-azhar University
4ENT Department, faculty of Medicine for Girls (cairo), Al-azhar university.
Journal Title:International Journal of Medical Arts
Background: Involvement of the brainstem in multiple sclerosis [MS] has significant implications on the disease course and can be presented with different symptoms. There are many tests able to detect brain-stem involvement in MS with various degrees of success.
Aim of the work: To study the changes in vestibular evoked myogenic potential [VEMP], in patients with MS, and to detect its sensitivity for detection of the brain-stem lesions previously diagnosed with magnetic resonance imaging [MRI] in MS patients.
Patients and Methods: Sixty participants had been enrolled and divided into two groups: 30 healthy subjects [Control group] and 30 MS patients [Study group]. Both groups had been subjected to otological examinations, pure tone audiometry, acoustic impedance, cervical vestibular evoked myogenic potential [cVEMP], ocular vestibular evoked myogenic potential [oVEMP] and MRI.
Results: In MS group, oVEMP mean latencies of n1 and p1 and cVEMP mean p13 and n23 latencies were significantly prolonged. In addition, 14 MS patients [46.7%] had brainstem lesions as confirmed by MRI. Finally, oVEMP test had higher sensitivity than the cVEMP in prediction of brainstem lesions.
Conclusion: oVEMP seems to be useful and more sensitive than cVEMP as an adjunct test in the evaluation of brain-stem dysfunction in MS patients.