• We are available for your help 24/7
  • Email: info@isindexing.com, submission@isindexing.com


Paper Details

Effect of Sublingual Misoprostol Prior to Insertion of Intrauterine Device in Women with no Previous Vaginal Delivery  

Zeinab Mohamed Elgharbawy  1; Abd Elraouf Mohamed Oun2; Waleed Ahmed Ayad3 1Department of Obstetrics and Gynecology, Port Fouad General Hospital, Ministry of Health and Populations, Egypt 2Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt. 3Department of Obstetrics and Gynecology, Dameitta Faculty of Medicine, Al-Azhar University, Egypt.  

Journal Title:International Journal of Medical Arts
Abstract


Background: The intrauterine device [IUD] is a safe and effective method of contraception, fear of pain during insertion discourages some providers to recommend IUDs to women with no previous vaginal delivery.  Aim of the work:The aim of the study is to evaluate sublingual misoprostol 200µg on the cervix one hour before IUD insertion; to facilitate IUD insertion in women with tight cervix or in whom did not deliver vaginally. Patients and Methods:The study was a double blinded randomized controlled trial, compared sublingual 200µg misoprostol with placebo. The study included 260 cases attended the Gynecology Clinic [Al-Azhar University Hospital] from December 2018 to November 2019. All females signed an informed written consent, and then have been randomly divided into 2 groups using a closed envelope technique. Every female had been asked to take the drug sublingually then return after one hour to insert her IUD. Group A included 130 females who used sublingual misoprostol 200µg [Misotac] and group B included 130 females who took a placebo one hour before IUD insertion [Control group]. Results: IUD and uterine sound insertion was unsuccessful in 8.5% of group A versus 13.8% in group B while it was successful in 91.5% of group A versus 86.2% in Group B. Among the successful cases, 88[73.9] were easy in group A versus 77[68.8] in group B. On the other hand, 31[26.1%] and 35[31.2%] were difficult in group A and B respectively. With no significant difference between both groups either in IUD or uterine sound insertion successful or easiness rate [p=0.17 & 0.38 respectively] Conclusion: Using of misoprostol to facilitate IUD insertion in women with tight cervix, has no role in pain reduction or increase the ease of IUD insertion, although results with misoprostol are superior to placebo, but the different did not reach statistical significance  

Download